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Meiler Lab Computational Chemical and Structural Biology |
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Group Members
Georg Kuenze
Current research Professor
PhD in Biochemistry University of Leipzig, Germany
georg.kuenze [ at ] vanderbilt.edu
Research Interests:
- NMR spectroscopy with paramagnetic probes
- Integrative modeling of membrane proteins and protein complexes with Rosetta
- Computational simulations and drug discovery on ion channels
- PET tracer binding to tau fibril structures
Georg is currently team leader of the junior group 'Computational Structural Biology' at the Institute for Drug Discovery at Leipzig University.
Visit the Künze Lab website to find out more: https://www.kuenzelab.org/
Publication List:
- Research Projects
- Publications
Hui Huang;G Kuenze, JA. Smith, KC. Taylor, AM. Duran, A Hadziselimovic, Jens Meiler, Carlos G. Vanoye, Alfred L. George Jr, C R. Sanders
Mechanisms of KCNQ1 channel dysfunction in long QT syndrome involving voltage sensor domain mutations (2018) Science advances
Manasi P Bhate;Thomas Lemmin, Georg Kuenze, Bruk Mensa, Soumya Ganguly, Jason Peters, Nathan Schmidt, Jeffrey G. Pelton, Carol Gross, Jens Meiler, and William F. DeGrado
Structure and function of the transmembrane domain of NsaS, an antibiotic sensing histidine kinase in S. aureus (2018) JACS
Joedicke L;Mao J, Kuenze G, Reinhart C, Kalavacherla T, Jonker HRA, Richter C, Schwalbe H, Meiler J, Preu J, Michel H, Glaubitz C
The molecular basis of subtype selectivity of human kinin G-protein-coupled receptors. (2018) Nat Chem Biol.
Xia Y;Ledwitch K, Kuenze G, Duran A, Li J, Sanders CR, Manning C, Meiler J
A unified structural model of the mammalian translocator protein (TSPO) (2019) J Biomol NMR
Mechanisms of KCNQ1 channel dysfunction in long QT syndrome involving voltage sensor domain mutations (2018) Science advances
Manasi P Bhate;Thomas Lemmin, Georg Kuenze, Bruk Mensa, Soumya Ganguly, Jason Peters, Nathan Schmidt, Jeffrey G. Pelton, Carol Gross, Jens Meiler, and William F. DeGrado
Structure and function of the transmembrane domain of NsaS, an antibiotic sensing histidine kinase in S. aureus (2018) JACS
Joedicke L;Mao J, Kuenze G, Reinhart C, Kalavacherla T, Jonker HRA, Richter C, Schwalbe H, Meiler J, Preu J, Michel H, Glaubitz C
The molecular basis of subtype selectivity of human kinin G-protein-coupled receptors. (2018) Nat Chem Biol.
Xia Y;Ledwitch K, Kuenze G, Duran A, Li J, Sanders CR, Manning C, Meiler J
A unified structural model of the mammalian translocator protein (TSPO) (2019) J Biomol NMR