• Protein Structure Prediction
• Sparse EPR Data guided Protein Structure Elucidation
• Protein Structure Prediction using Fold Templates
• Gradient Minimization for Structure Refinement

Axel Fischer;Nathan Alexander, Nils Woetzel, Mert Karakas , Brian E. Weiner, Jens Meiler
BCL::MP Fold: Membrane protein structure prediction guided by EPR restraints (2015) Proteins

Sten Heinze;Daniel K. Putnam, Axel W. Fischer, Tim Kohlmann, Brian E. Weiner, and Jens Meiler
CASP10-BCL::Fold efficiently samples topologies of large proteins (2015) Proteins

Tommy Hofmann;Axel W. Fischer, Jens Meiler, and Stefan Kalkhof
Protein structure prediction guided by crosslinking restraints – A systematic evaluation of the impact of the crosslinking spacer length (2015) Methods

Reza Dastvan;Axel W. Fischer, Smriti Mishra, Jens Meiler, and Hassane S. Mchaourab
Protonation-dependent conformational dynamics of the multidrug transporter EmrE (2015) Proceedings of the National Academy of Sciences Journal (PNAS)

Axel Fischer;Sten Heinze, Daniel Putnam, Bian Li, James Pino, Yan Xia, Carlos Lopez, Jens Meiler
CASP11-An Evaluation of a Modular BCL::Fold-Based Protein Structure Prediction Pipeline (2016) PLOSone

Axel Fischer;Enrica Bordignon, Stephanie Bleicken, Ana Garcia-Saez, Gunnar Jeschke, Jens Meiler
Pushing the size limit of de novo structure ensemble prediction guided by sparse SDSL-EPR restraints to 200 residues: The monomeric and homodimeric forms of BAX (2016) Journal of Structural Biology

Maximiliano Figueroa;Mike Sleutel, Marylene Vandevenne, Gregory Parvizi, Sophie Attout, Olivier Jacquin, Julie Vandenameele, Axel Fischer, Christian Damblon, Erik Goormaghtigh, Marie Valerio-Lepiniec, Agathe Urvoas, Dominique Durand, Els Pardon, Jan Steyaert, Philippe Minard, Dominique Maes, Jens Meiler, Andre Matagne, Joseph Martial, Cecile Van de Weerdt
The unexpected structure of the designed protein Octarellin V.1 forms a challenge for protein structure prediction tools (2016) Journal of Structural Biology

Li B;Mendenhall J, Nguyen ED, Weiner BE, Fischer AW, Meiler J.
Improving prediction of helix-helix packing in membrane proteins using predicted contact numbers as restraints (2017) Proteins

Xia Y;Fischer AW, Teixeira P, Weiner B, Meiler J.
Integrated Structural Biology for ?-Helical Membrane Protein Structure Determination. (2018) Structure

Axel W. Fischer;David M. Anderson, Maxx H. Tessmer, Dara W. Frank, Jimmy B. Feix, and Jens Meiler
Structure and Dynamics of Type III Secretion Effector Protein ExoU As determined by SDSL-EPR Spectroscopy in Conjunction with De Novo Protein Folding (2017) ACS Omega

Bian Li;Jeffrey Mendenhall, Elizabeth Dong Nguyen, Brian E. Weiner, Axel Fischer, and Jens Meiler
Accurate Prediction of Contact Numbers for Multi-Spanning Helical Membrane Proteins (2016) Journal of Chemical Information and Modeling

Axel Fischer;Tommy Hofmann, Jens Meiler, Stefan Kalkhof
Protein structure prediction guided by crosslinking restraints – A systematic evaluation of the impact of the crosslinking spacer length (2015) Methods